FLASHLAB
Electron FLASH Irradiator for
Translational Research in Radiobiology
Introducing FLASHLAB®, the latest addition to our range of FLASH technology linear accelerators, offering capabilities in UHDR (Ultra-High Dose Rate) electron beam delivery for research in radiobiology. FLASHLAB is an investigational device designed to explore the mechanisms of the FLASH effect, bringing new possibilities for translational research and potential clinical applications of FLASH radiotherapy.
- Compact device for easy addition and integration into bunkers and research facilities
- Ultra-high dose rate (UHDR), 7MeV radiation head, able to deliver dose rates up to 300 Gy/s
- 10 cm field size
- R80 from 20 to 25 mm
A Decade of Expertise: Building on the Legacy of Oriatron eRT6
FLASHLAB is the result of over a decade of research and development into the FLASH effect, leveraging expertise initially established with the Oriatron eRT6 Linac prototype installed at Lausanne University Hospital (CHUV) in Switzerland. This pioneering prototype laid the foundation for FLASHLAB’s advanced design through a number of studies supported by the Oriatron. These research findings have driven the innovation behind FLASHLAB, creating a tool able to further contribute cutting-edge investigation into FLASH radiotherapy on a larger scale.
Research papers supported by the Oriatron eRT6
- Vozenin, M. et al. (2018b). The Advantage of FLASH Radiotherapy Confirmed in Mini-pig and Cat-cancer Patients. Clinical Cancer Research, 25(1), 35–42.https://doi.org/10.1158/1078-0432.ccr-17-3375
- Bourhis, J. et al. (2019). Clinical translation of FLASH radiotherapy: Why and how? Radiotherapy and Oncology, 139, 11–17. https://doi.org/10.1016/j.radonc.2019.04.008
- Bourhis, J et al. (2019). Treatment of a first patient with FLASH radiotherapy. Radiotherapy and Oncology, 139, 18 22. https://doi.org/10.1016/j.radonc.2019.06.019
Did you know?
The primary use of the Oriatron linear accelerator, developed by PMB-ALCEN, is non-destructive testing. It was only in 2014, when Vincent Favaudon’s research inspired further studies of the FLASH effect requiring innovative technology capable of triggering it, that the Oriatron was configured to be capable of delivering radiation at Ultra High Dose Rates.
Purpose-built for research into the FLASH effect
As an investigational device, FLASHLAB is engineered to allow irradiation at an ultra-high dose rate within timeframes consistent with triggering the FLASH effect. This capability allows for targeted studies on the various potential radiobiological mechanisms of which the understanding would support the use of clinical translation FLASH radiotherapy in clinical settings.
FLASHLAB’s dimensions
| Designation | Length (mm) | Width (mm) | Height (mm) | Weight (kg) |
|---|---|---|---|---|
| Radiation Head | 1,245 | 720 | 1,210 | 485 |
| Cooling Unit | 1,100 | 780 | 1,700 | 250 |
| Power Supply & Electronics Cabinet | 900 | 600 | 1,800 | 250 |
| User Interface: PC & Safety Control Box | Desktop PC & Console | |||
Interested in Advancing Research into the FLASH effect?
FLASHLAB is now available for installation as a dedicated research tool, ready to empower laboratories with the means to explore the FLASH effect.
Get in touch with our team and find out how FLASHLAB can support your studies in FLASH radiobiology.