Physics World
VHEE could prove optimal for FLASH radiotherapy

THERYQ is developing a radiotherapy device that would use Very-High Energy Electrons (VHEE) to treat deep-seated tumors, and can also enable FLASH treatments.
Studies and clinical trials using devices intended for the irradiation of superficial lesions have repeatedly encouraged the eventual widespread integration of FLASH Radiotherapy into clinical routine.¹

But what if we could take the benefits of FLASH even further, and reach depths where no electrons have gone before? That is where FLASH Radiotherapy using Very-High Energy Electrons (VHEE) comes in.

The use of Very-High Energy Electrons together with FLASH Radiotherapy could be the key to going beyond both the limitations of conventional radiotherapy and the depth limitations of low-energy beams.² Initial studies show that when electron beams reach energy levels of over 50MeV, they carry characteristics favorable to clinical applications.³

Read the full article on Physics World to find out more about the value carried by the VHEE & FLASH combination, with insights from leading experts in the field of VHEE-FLASH radiotherapy: https://physicsworld.com/a/very-high-energy-electrons-could-prove-optimal-for-flash-radiotherapy/

References

1. Vozenin, MC.; Bourhis, J. & Durante, M. Towards clinical translation of FLASH radiotherapy. (2022) Nat Rev Clin Oncol 19, 791–803 https://doi.org/10.1038/s41571-022-00697-z

2. Böhlen, T.T.; Germond, J.-F.; Traneus, E.; Bourhis, J.; Vozenin, M.-C.; Bailat, C.; Bochud, F. & Moeckli, R., Characteristics of very high-energy electron beams for the irradiation of deep-seated targets (2021). Med. Phys., 48: 3958-3967. https://doi.org/10.1002/mp.14891

3. Panaino, C.M.V.; Piccinini, S.; Andreassi, M.G.; Bandini, G.; Borghini, A.; Borgia, M.; Di Naro, A.; Labate, L.U.; Maggiulli, E.; Portaluri, M.G.A.; et al. Very High-Energy Electron Therapy Toward Clinical Implementation. (2025) Cancers, 17, 181. https://doi.org/10.3390/cancers17020181